Jag har identifierat tre typer av det enzym som används för att kopiera DNA som fungerar bättre i närvaro av andra substanser än den enzymvariant som används som standard inom kriminaltekniken i dag.
Vad är syftet med din forskning?
Inom kriminaltekniken utgår man ofta från prover som innehåller relativt lite DNA och som dessutom är nedsmutsade av andra substanser. Det kan till exempel vara ett prov från en cigarettfimp som innehåller både papper och ämnen från tobaken. För att kunna analysera DNAt i provet kopierar man upp det med hjälp av enzymet DNA-ploymeras. Problemet är att DNA-plomeraset störs om det finns andra molekyler än DNA i provet. I dag försöker man därför rena sina prov så mycket som möjligt vilket är en arbetsam process. Att rena upp provet innebär också att man förlorar genetiskt material på vägen. Därför ville jag hitta ett mer robust sätt att hantera provet.
Vad har du kommit fram till?
Jag har screenat olika DNA-polymeras och hittat tre stycken som fungerar bättre än det enzym som används över hela världen i dag. Jag har också optimerat buffert, pH och jonsammansättning för dessa tre enzym och testat dem på 32 prov i Statens Kriminaltekniska Laboratorium, SKLs, arkiv. Med dagens metod gick det inte att få fram några användbara DNA-profiler ur proven men med min metod gick det att använda 28 av proven.
Vad hoppas du dina resultat ska användas till?
Framför allt vill jag att folk ska få upp ögonen för att de standardmetoder man använder kanske inte alltid är de bästa. Ja blev själv förvånad över att det blev så bra resultat som det blev med min metod, man tänker sig liksom att reaktionen är som den är och att den inte går att förbättra. Det ska bli intressant att se vad vi får för respons från andra kriminaltekniska labb i världen eftersom det här är ett lite nytt tankesätt.









































"To supply Swedish and Danish laboratories with laboratory equipment and furniture of highest quality and offer service on all delivered products."
"Our reliability, customer service, global network and integrated technology make World Courier service truly "A service no one else can deliver"."
"Our aim is to be the best drug development partner to the biotechnology and pharmaceutical industry no matter where you are based."
"Your global partner of pharmaceutical service and cGMP manufacturing"
"We help our clients create significant business value through scientific expertise."
"Best in class companies see the value of optimising their business by having an effective strategy for information management and documentation."
"Dilafor is developing new products in the field of obstetrics, to provide an effective solution to the challenge of dystocia or protracted labor"
"
"VWR is a global laboratory distributor of chemicals, life science products, consumables, equipment, instruments, furniture, e-commerce and services"
"Uppsala BIO is a life science pathfinder. We build ways to make life science flourish, in cooperation with industry, academia, society and healthcare."
"To be the most attractive node and business platform in the Nordic countries for new and innovative Life Science companies"
"Novel products for CVD treatment and prevention."
"We have a unique technological platform, built around 5HT-receptor antagonism, for the treatment of inflammation and pain"."
"We promise to go the extra mile every day to ensure you receive the highest level of service and value with each shipment you entrust to us."
"TFS is today the leading European development partner for biopharmaceutical companies in their global clinical development process."
"Our organisation value is to contribute to positioning Scandinavian healthcare and research in absolute world class."
"PCG - a professional full service CRO for your clinical trials.
Powered by Viedoc, globally trusted eCRF, keeping trials within budget and timelines"
"We are recognized as a flexible partner with short decision and lead times plus a proven record for the highest quality and cost efficiency."
"Our vision is to become one of the top 10 global providers of scientific instruments; we will get there by striving for market leadership in our respective product and application niches."
"
"Discover your possibilities in one of Europe´s most productive life science regions. Welcome to Stockholm-Uppsala."
"
"The PolyPeptide Group is a world class manufacturer of peptide active pharmaceutical ingredients."
"With our first class products and our committed and skilled colleagues we guarantee our customers the best support in the market, at no extra charge."
"Our products enable an increased number of transplants leading to substantial cost savings for society and increased quality of life for patients."
"We offer effective staffing solutions provided by specialists, we understand a company’s specific needs and we know where to find the best talent."
"We turn medical research into applications for better health and well-being."
"Innovation takes place when biology meets engineering; ICT is an enabler to solve the needs for increased functionality and reduced cost in Life Science"
"Allenex is a life science company that develops, manufactures, markets and sells high quality products for the transplantation market."
"We are making it more attractive for companies to invest in innovation with reduced corporation tax on profits from patents to 10%."
"Medivir is a specialty pharmaceutical company with unique positioning on the Nordic market and our goal is become a profitable company in high growth"
"Your work is important to us, we are committed to your success.
Innovative tools? Please download the Promega app."
"To develop innovative and effective pharmaceuticals within autoimmune/ inflammatory diseases and cancer where major medical need exists"
"Mercodia has been a supplier of reliable assays since 1991"
"Anton Paar is a product and service leader in the field of scientific instruments. We deliver uncompromised quality in everything we do."
"We are entirely devoted to luminescence technology."
"APL provides high-quality services to Life Science. We are a Dedicated Partner from Discovery to Market."
"Our services in ligand-based and structure-based drug design is a cost-efficient alternative for smaller pharmaceutical companies"
"As a full service CRO with offices in all Nordic countries we can provide our customer with professional support throughout the clinical research."
"We aim to be the pioneering benchmark in user-friendly software experience in combination with the highest level of quality."
"Our goal is to invest in innovations and develop new unique pharmaceuticals"
"To adapt Competent Authorities´ requirements into opportunities is not just an artform - today it´s a business necessity." 
