Sommaren 2008 krävde tolv framstående läkare en ändring: ”Detta innebär att stora grupper av patienter med allvarliga och livshotande akuta sjukdomar är förhindrade att deltaga i forskningsprojekt som strävar till att utveckla och förbättra behandlingen av dessa tillstånd. Exempel på sådana tillstånd är medvetslöshet på grund av skallskador, hjärtstillestånd eller svåra infektioner men även vid akuta psykoser och andra tillstånd där patienten kan bedömas som beslutsoförmögen.”
Det hela löste sig genom ett till-ägg från 2008 i lagen om etikprövning, där forskning utan samtycke får genomföras ”om forskningen kan förväntas ge en kunskap som inte är möjlig att få genom forskning med samtycke, och om forskningen kan förväntas leda till direkt nytta för forskningspersonen.”
Även om det sista villkoret inte uppfylls, kan forskningen utföras om syftet är att bidra till ett resultat som kan vara till nytta för forskningspersonen eller någon annan som lider av samma sjukdom eller störning, och om den innebär en obetydlig risk för skada och obehag för forskningspersonen. Allt givetvis efter tillstånd från Läkemedelsverket och sedvanlig etikprövning.
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