Plattformen som utvecklats av Applied Biosystems har bland annat utrustats med termoblock som är enkla att byta ut, vilket gör att block för en rad olika typer av plattor kan användas. Bland annat kan Quantstudio analysera Openarray-plattor, Taqman-arraykort, 384-brunnsplattor och 96-brunnsplattor. Detta gör att de flesta typer av realtidsexperiment kan köras på systemet. Plattformen levereras med en intuitiv mjukvara och kan enkelt konfigureras via den inbyggda pekskärmen. Det går också att integrera Quantstudio i automatiserade arbetsflöden för att minimera arbetet vid användning. Fem olika utbytbara block följer med plattformen, och beroende på analysformat kan från 1 till 12000 datapunkter erhållas vid varje körning.
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