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Det svenska forskningsbolaget Neurovive samarbetar med det holländska bolaget To-BBB om att utveckla en läkemedelskandidat för behandling av stroke. Nu meddelar de båda parterna att utvecklingsprojektet går in i preklinisk fas.
I samarbetet står Neurovive för den aktiva substansen cyklosporin-A, ett ämne som verkar nervcellskyddande. To-BBBs bidrag i samarbetet är en teknik som kan användas för att transportera läkemedel genom blod-hjärnbarriären och möjliggöra behandling av sjukdomar i hjärnan.
Genom att koppla ihop de båda bolagens kompetens har de tagit fram en formulering av cyklosporin-A som kan gå igenom blodhjärnbarriären. Formuleringen ska nu testas i prekliniska studier genom ett nytt samarbete med två finska företag som arbetar med att testa nya läkemedel i prekliniska modellsystem för stroke.
I samarbetet står Neurovive för den aktiva substansen cyklosporin-A, ett ämne som verkar nervcellskyddande. To-BBBs bidrag i samarbetet är en teknik som kan användas för att transportera läkemedel genom blod-hjärnbarriären och möjliggöra behandling av sjukdomar i hjärnan.
Genom att koppla ihop de båda bolagens kompetens har de tagit fram en formulering av cyklosporin-A som kan gå igenom blodhjärnbarriären. Formuleringen ska nu testas i prekliniska studier genom ett nytt samarbete med två finska företag som arbetar med att testa nya läkemedel i prekliniska modellsystem för stroke.
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