Biovitrum's candidate drug, BVT 28949 is a serotonin receptor 2A antagonist (5-HT2A) antagonist for the treatment of glaucoma. Phase I studies began in September 2005 on 64 healthy volunteers.
The present Phase II study includes 150 patients with an elevated intraocular
pressure (a hallmark of glaucoma) and the study is estimated to be completed
during spring 2007 with results available in the middle of the year. The Phase
II study is placebo-controlled and is carried out at several clinics in Sweden and Ukraine.
It is estimated that nearly 70 million people worldwide suffer from glaucoma, which is the leading cause of blindness in the developed world. The total market value for this type of medicines amounts to approximately $3.9 billion.
BVT.28949 is a selective 5-HT2A antagonist which could be suitable for administration in the form of eye drops.
The present Phase II study includes 150 patients with an elevated intraocular
pressure (a hallmark of glaucoma) and the study is estimated to be completed
during spring 2007 with results available in the middle of the year. The Phase
II study is placebo-controlled and is carried out at several clinics in Sweden and Ukraine.
It is estimated that nearly 70 million people worldwide suffer from glaucoma, which is the leading cause of blindness in the developed world. The total market value for this type of medicines amounts to approximately $3.9 billion.
BVT.28949 is a selective 5-HT2A antagonist which could be suitable for administration in the form of eye drops.
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